5-Hydroxytryptophan (5-HTP) is an intermediate in the natural synthesis of the essential amino acid, tryptophan, to serotonin. The enzyme tryptophan hydroxylase adds a hydroxyl group (OH) to tryptophan, forming the 5-HTP intermediate. In the body, it converts to serotonin with the removal of a carboxyl group (COOH) by a second enzyme. Serotonin is an important neurotransmitter involved in the regulation of endocrine and brain activity responsible for emotion, appetite and sleep/wake cycles. In clinical studies, administration of 5-HTP supported serotonin production. The 5-HTP supplied in this supplement is derived from the Griffonia simplicifolia plant.
Pure Encapsulations was founded to formulate and manufacture the highest quality line of hypo-allergenic supplements available. Since our inception, we have been the industry leader in manufacturing excellence and quality control, as well as a pioneer in the production of research-based and clinically relevant formulas. There are currently nine clinical trials in progress involving Pure Encapsulations products, including studies at Stanford University, Michigan State and the Mayo Clinic.
In 2004, Pure was acquired by Atrium Innovations Inc. Atrium Innovations Inc. is a recognized leading developer, manufacturer and marketer of science-based and professionally endorsed products for the health and nutrition industries.
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